In this presentation, Purilogics by Donaldson introduces the concept of using high-performance membrane chromatography technologies to rapidly purify SC pDNA and mRNA. We will illustrate purifying SC pDNA by capture chromatography using Purexa™ NAEX Plus, a weak anion chromatography membrane, followed by a polishing step using Purexa™ MCP, a hydrophobic interaction chromatography membrane that has superior and consistent capability to separate SC pDNA from open circular pDNA. We will illustrate purifying mRNA using Purexa™ OdT, an affinity capture chromatography membrane targeting the Poly A tails in mRNA.

Purilogics is excited to attend ACS Spring 2019 in Orlando. We would love to talk shop about your purification challenges! Come visit us at our posters 6-8pm April 2nd to see the latest data on our multimodal anion exchange and Protein A membrane chromatography prototypes.