Addressing the Plasmid DNA Manufacturing Bottleneck
Over the past few years, we have seen a steady increase in the demand for plasmid DNA, as the gene and cell therapy industries have experienced rapid growth…
Why is Membrane Chromatography Faster Than Resin Chromatography?
Imagine a glass holding sugar. After adding water, it is left to sit. Ultimately, the sugar will dissolve after a few hours…
How Does Flow Rate Affect the Binding Capacity of Purexa™ Membranes?
At Purilogics, we take pride in designing and developing membrane chromatography technologies for biologics purification. Our mission is to provide rapid and effective purification solutions to help the biopharmaceutical industry simplify biologics purification.
Polishing Step Purification of mAbs using Purexa™ MQ
Purilogics®’ PurexaTM-MQ multimodal anion-exchange chromatography membrane is differentiated by its high binding capacity and effectiveness in removing impurities such as host cell proteins, virus particles, DNA, and aggregates from biologic products under conditions of high solution conductivity…
What are Virus-Like Particles?
Since interest is growing in the area of virus-like particles (VLPs), we would like to share some notes on what we’ve found in our research, Purilogics would like to highlight a few of our products that are well-suited for purification of VLPs…
What do We Know about HCPs – Learning from Literature (1)
Host cell proteins (HCPs) refer to a broad spectrum of proteins produced by the cells in which the product of interest is made. HCPs are process related impurities and are one of many critical quality attributes. Both the FDA and EMA require residual HCP to be reduced to an acceptable level.
Monoclonal Antibody (mAb) Aggregates: When do they form?
In our second post on monoclonal antibody (mAb) aggregates, we’ve collected some more details about how and under what conditions mAbs may aggregate…
A Snapshot of Progress in mRNA and DNA vaccines
Vaccines are prophylactics designed to safely introduce epitopes of bacteria or viruses to your immune system to stimulate a response unique to the antigen…
Aggregates Removal in Monoclonal Antibody Purification
The presence of aggregates in therapeutic monoclonal antibody (mAb) drugs is a major concern because they can decrease product efficacy and cause an immunogenic response in patients…
AAV Purification Book Notes (1)
Purilogics® develops novel membrane adsorbers for biologics purification. Unlike other high capacity membrane products, PurexaTM membrane products are differentiated by their tentacle based ion-exchange ligands.